We are pleased to share an important milestone: 50% of the planned patients have now been enrolled in the study, bringing the trial halfway toward the accrual goal of 411 patients

We would like to thank all the patients who have chosen to participate in this definitive study, as well as the Principal Investigators, investigators and clinical sites across Europe, and partners whose dedication and collaboration make this achievement possible. This milestone was made possible by dedicated patients and professionals, real effort, and a shared commitment […]
Video featuring Professor Matthias Preusser, Principal Investigator and Co-Leader of LEGATO

We’re excited to share a video featuring Professor Matthias Preusser, Principal Investigator and Co-Leader of LEGATO. Produced by the EU Mission on Cancer (Horizon Europe), the video outlines the project’s next steps, goals and expected impact. The EU Mission on Cancer – part of Horizon Europe – aims to “improve the lives of more than […]
Introducing the Top Recruiters of the LEGATO Trial – Professor Giuseppe Lombardi, MD, PhD

Professor Giuseppe Lombardi, MD, PhD, is a medical oncologist at the IOV – Istituto Oncologico Veneto– Veneto Institute of Oncology in Padua, Italy, where he is currently recruiting patients for the LEGATO study. A leading clinical researcher in the field of neuro-oncology, Professor Lombardi has been deeply involved in advancing brain tumor treatment for over […]
Introducing the Top Recruiters of the LEGATO Trial – Professor François Ducray, MD, PhD

Professor François Ducray, MD, PhD, is a neuro-oncologist at the HCL – Hospices Civils de Lyon and the Centre de Recherche en Cancérologie de Lyon (CRCL) in Lyon, France, where he is currently recruiting patients for the LEGATO study. An active leader in clinical research, Professor Ducray is the local principal investigator and/or national coordinator […]
Tomas Kazda, M.D., Ph.D. – Young Investigator of the LEGATO Project

Tomas Kazda is the Director of Research, Science, and Education at the Masaryk Memorial Cancer Institute in Brno, Czechia, and the Chief of the Radiotherapy Program for Brain Tumors at the same institution. He is a member of several scientific boards and expert committees, including the EORTC Brain Tumor Group. He graduated from Masaryk University, […]
The objectives of the LEGATO Project in the words of Principal Investigator and Co-Leader Prof. Dr Matthias Preusser

LEGATO is part of a series of clinical trials funded by the Horizon Europe programme as part of the EU Mission on Cancer. The twelve clinical trials, led by multistakeholder and multidisciplinary consortiums, form together the European Cancer Cluster. In this video, the project’s Principal Investigator and Co-Leader, Prof. Dr Matthias Preusser from the Medical […]
Introducing the Clinical Trial leaders of the LEGATO Project, Prof. Dr Matthias Preusser and Prof. Dr Giuseppe Minniti

Over the last couple of months, we introduced the people and organisations behind the LEGATO Project on our social media platforms. In this article, we will focus on the project’s clinical trial leader, Prof. Dr Matthias Preusser, and the clinical trial co-leader, Prof. Dr Giuseppe Minniti. Dr Preusser is Professor of Medical Oncology and Head of […]
Official start of project LEGATO

The European Organisation for Research and Treatment of Cancer (EORTC) and the Syreon Research Institute are delighted to announce the official start of LEGATO, a pragmatic phase III clinical trial focusing on recurrent Glioblastoma. This is the first official trial looking into the potential benefits of chemo-irradiation compared to chemotherapy alone to improve disease control […]